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Glucose basics

Why blood sugar is high when you're sick


Dec. 5, 2024 4 min read

Sick woman sitting on couch blowing nose
The content in this article should not be taken as medical advice. Please consult with your healthcare provider regarding your individual health needs.

Have you ever wondered why your blood sugar levels suddenly go up when you’re sick, even if you’re keeping an eye on your diet? When you’re feeling under the weather, your body is dealing with a lot more than just the symptoms you notice. The truth is, your body’s response to illness is surprisingly complex, especially when it comes to managing glucose.
Let’s examine what happens in your body during illness, why glucose spikes are so common, and what you can do to manage your glucose levels.

Your body’s natural stress response

When you catch a cold, the flu, or any other infection, it triggers a stress response in your body. This is a natural, protective reaction designed to help you fight off the illness. Your body releases stress hormones like adrenaline (also known as epinephrine) and cortisol, which signal your liver to release extra glucose into your bloodstream. This provides a quick source of energy for your immune system to combat the infection.
Unfortunately, this increase in glucose can be problematic if your body is struggling with insulin resistance or if you’re not producing enough insulin. High-stress hormones make your cells less responsive to insulin, meaning the insulin can’t effectively move glucose out of your bloodstream and into your cells. This is why your blood sugar may be high when you’re sick.

The role of inflammation

Illness often brings inflammation, another natural process that helps your body fend off bacteria and viruses. However, inflammation can also make your cells more resistant to insulin. This reduced insulin sensitivity can lead to more glucose staying in your bloodstream than usual, which contributes to higher blood sugar levels.

Changes in eating, activity, and medication

When you're ill, your regular habits around food and activity often shift too. Maybe you’re eating less, or maybe you’re craving comfort foods that aren’t in your usual routine. You might also be more sedentary, resting on the couch or staying in bed. All of these changes can affect your blood sugar.
Certain cold medications, especially those containing decongestants or sugars, can also elevate glucose. Decongestants may trigger glucose release from the liver, while cough syrups and lozenges often contain sugar, which can also contribute to unexpected spikes. If you’re on steroids, such as prednisone, to manage inflammation, you may experience even more significant increases in blood sugar.
It’s always wise to check in with a pharmacist or your healthcare provider before taking any new medications to ensure they won’t interfere with your glucose management.


Feel better
When you’re sick, remember that it’s okay to slow down and take extra care of yourself. Even though managing blood sugar on sick days can be a challenge, these strategies can help you stay on top of it, so you can focus on what matters most: feeling better.



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